Examples of proteins
More ... Consult our list of links on protein structure
Much, much more on the MBN CD-ROM
Biology book: proteins and synthesis of
proteins
Use for educational purposes is heartily encouraged.
Date reviewed: 23/04/99
CATH: Protein Structure Classification
CATH is a novel hierarchical classification of protein
domain structures, which clusters proteins at four major levels, class(C),
architecture(A), topology(T) and homologous superfamily (H). Class, derived from
secondary structure content, is assigned for more than 90% of protein structures
automatically. Architecture, which describes the gross orientation of secondary
structures, independent of connectivities, is currently assigned manually. The
topology level clusters structures according to their toplogical connections and
numbers of secondary structures. The homologous superfamilies cluster proteins
with highly similar structures and functions. The assignments of structures to
toplogy families and homologous superfamilies are made by sequence and structure
comparisons.
Date reviewed: 13/10/99
Cis-Peptide Bonds in Proteins
The IMB Jena Image Library of Biological Macromolecules
contains visual and other information on three-dimensional biopolymer
structures. It provides access to all structure entries deposited at the Protein
Data Bank (PDB) or at the Nucleic Acid Database (NDB).
Data can be complexe for the beginner
Date reviewed: 14/01/99
How do enzymes work
A collection of experiments which show how enzymes work.
Date reviewed: 22/01/99
IMB Jena Image Library of Biological Macromolecules
The IMB Jena Image Library of Biological Macromolecules
contains visual and other information on three-dimensional biopolymer
structures. It provides access to all structure entries deposited at the Protein
Data Bank (PDB) or at the Nucleic Acid Database (NDB). In addition, general
information on the architecture of biopolymer structures is available.
The information deposited there can be a bit overwhelming
for the beginner.
Date reviewed: 14/01/99
Introduction to Protein Structure
This project develops, tests and incorporates into
introductory chemistry and biology courses a series of modules based on
important scientific themes: molecular aspects of biological structures, bonding
and intermolecular forces, dynamics including enzymes and catalysis, aspects of
equilibria especially acids and bases, energy and thermodynamics, organic
reaction mechanisms especially metabolism, and bioethics.
Requires Chime plug in
Date reviewed: 21/07/00
NDB Biological Structure Resource (BSR)(The)
This site is a selection of databases, containing
information about structure and other features of proteins and nuckleic acids.
Good source of material.
Date reviewed: 22/01/99
Principles of Protein Structure Using the Internet
The Advanced Certificate in the Principles of Protein
Structure using the Internet, is a tutor-assisted, university-level, accredited
course. The course exploits modern developments in communications, which means
that students from any country may study the course at home, at work or in a
university.
Date reviewed: 27/01/99
Principles of Protein Structure Using the
Internet
Much of the course material has been written specifically
for the PPS course (before or during last year's run) by a large number of
different authors around the world, and in general the material is available at
the Web-site where it was written.
Date reviewed: 21/07/00
Protein Architecture tutorials
The Lehninger 3D Structure Tutorials are designed to
accompany Principles of Biochemistry, 3rd edition, by Lehninger, Nelson, and
Cox. They are built around the Chemscape Chime 2.0 plugin, which reads the
atomic coordinates of a biological macromolecule and renders it as a fully
interactive 3D structure.
Learn about all aspects of protein structure, from
the chemical properties of the amino acids to the interaction of multiple chains
in giant molecules.
Date reviewed: 20/11/01
Protein Data Bank: UK Mirror
The Protein Data Bank. A collection of files that
describe the three dimensional structure of mainly proteins and nucleic acids.
The PDB was managed entirely by BNL until the end of 1998. From 1 July 1999 it
has been managed in the USA by the RCSB.
Date reviewed: 28/02/01
Protein Information Resource
The Protein Information Resource (PIR), maintains the
PIR-International Protein Sequence Database --- a comprehensive, annotated, and
non-redundant set of protein sequence databases in which entries are classified
into family groups and alignments of each group are available.
Date reviewed: 18/03/99
Protein sequence analysis at UCL
Our research concerns protein sequence analysis,
primarily exploiting the technique of protein `fingerprinting' (which uses
conserved motifs to characterise particular folds and functionalities). We
maintain a database of fingerprints (PRINTS), which complements PROSITE. We aim
to improve fingerprint potency, to enhance predictive power in the Twilight
Zone. We also design software to display sequence and structural data in
visually-striking ways (e.g. using Java).
Very useful to have Java enabled when visiting this
site.
Date reviewed: 17/03/00
PROTEIN SOCIETY EDUCATIONAL INITIATIVE
Proteach: initiative to teach protein structure. Needs
plug in.
Date reviewed: 10/09/99
Scop: Structural Classification of Proteins
Welcome to scop: Structural Classification of Proteins.
Release 1.35. 5493 PDB Entries (3 Mar 97). 10781 Domains. 138 Literature
References.
Date reviewed: 22/01/99
Structural Elements of Proteins
The IMB Jena Image Library of Biological Macromolecules
contains visual and other information on three-dimensional biopolymer
structures. It provides access to all structure entries deposited at the Protein
Data Bank (PDB) or at the Nucleic Acid Database (NDB).
Data might be a bit complexe for the beginner. .
Date reviewed: 14/01/99
SWISS-PROT : Annotated Protein Database
SWISS-PROT is a curated protein sequence database which
strives to provide a high level of annotations (such as the description of the
function of a protein, its domains structure, post-translational modifications,
variants, etc), a minimal level of redundancy and high level of integration with
other databases (Disclaimer).
Date reviewed: 20/04/01
What is a prion?
what is known about the molecular structure of prions and
how they cause infections such as Creutzfeldt-Jakob disease?
Date reviewed: 29/03/00
Note: the email address mbn.online@bbsrc.ac.uk is no longer valid. If you
need help for MBN, please subscribe to molecular-biology-notebook forum. Thank
you
Pages designed and maintained by Nathalie Castells-Brooke , PhD.
Last
updated Tuesday, October 22, 2002.
Copyright Rothamsted Research, 1997 - 2002.
