Scientific Research
Effect of Creatine Loading
on
Neuromuscular Fatigue Threshold.
J. Appl. Physiol. 88: 109–112,
2000
Stout, Jeffrey, Joan Eckerson, Kyle Ebersole,
Geri
Moore, Sharon Perry, Terry Housh, Anthony Bull, Joel
Cramer, and Ash
Batheja.
The purpose of this investigation was to deter-minethe effect of creatine (Cr) loading on the onset of neuromuscular fatigue by monitoring electromyographic fa-tigue curves from the vastus lateralis muscle using the physical working capacity at the fatigue threshold (PWCFT) test. Using a double-blind random design, 15 women athletes [mean age 19.0 6 2.0 (SD) yr] from the university crew team received a placebo (n 5 8; 20 g glucose) or Cr (n 5 7;5 g Cr monohydrate 1 20 g glucose) four times per day for 5 consecutive days. Analysis of covariance was used to analyze the data (covaried for presupplementation PWCFT values). The adjusted mean postsupplementation PWCFT value for the Cr group (mean 5 186 W) was significantly (P , 0.05) higher than that of the placebo group (mean 5 155 W). These findings suggest that Cr loading may delay the onset of neuromuscular fatigue.
*Supported in part by FSI Nutrition Inc. Omaha, NE
